HLA-DPB2

Description

The HLA-DPB2 (major histocompatibility complex, class II, DP beta 2 (pseudogene)) is a pseudo gene located on chromosome 6.

HLA-DPB2 is a gene located on chromosome 6, within the major histocompatibility complex (MHC) class II region. It encodes a protein that forms part of the MHC class II complex, which is essential for presenting antigens to T cells, thereby triggering an immune response. This gene exhibits high polymorphism, with numerous variations observed in the population. These variations can influence an individual's susceptibility to certain diseases and their response to various treatments.

HLA-DPB2 is a gene that encodes a protein involved in the presentation of antigens to T cells. It is a member of the major histocompatibility complex (MHC) class II family, which plays a critical role in the immune system by recognizing and responding to foreign antigens. The protein encoded by HLA-DPB2 forms a heterodimer with the HLA-DPA1 protein, and this complex binds and presents peptide antigens to CD4+ T cells. This interaction initiates an immune response to eliminate pathogens. HLA-DPB2 is highly polymorphic, meaning that there are many different versions of the gene in the population. These different versions can influence the individual's susceptibility to certain diseases and their response to various therapies.

HLA-DPB2 is also known as DP2B, DPB2, DPbeta2, HLA-DP2B.

Associated Diseases

WES Whole Exome Sequencing

Clinical Exome Sequencing