HIST1H3J
Histamine: An Essential Mediator with a Dark Side
Description
Histamine is a vital chemical messenger (neurotransmitter) in the body, primarily responsible for regulating immune responses, gastric acid secretion, and airway constriction. It is a crucial player in both normal physiological functions and pathological processes.
Associated Diseases
Histamine dysregulation has been linked to various diseases, including:
- Allergies: Histamine release triggers allergic reactions, causing symptoms such as sneezing, runny nose, itchy eyes, and hives.
- Anaphylaxis: A severe, life-threatening allergic reaction caused by a sudden release of high levels of histamine.
- Asthma: Histamine causes airway constriction, leading to difficulty breathing and wheezing.
- Eczema: Histamine contributes to skin inflammation and itching in eczema.
- Gastric ulcers: Excess histamine stimulates gastric acid production, increasing the risk of ulcers.
Did you Know ?
- Approximately 10% of the global population is estimated to suffer from histamine intolerance, a condition characterized by an exaggerated response to histamine ingestion.