HIC2
Description
The HIC2 (HIC ZBTB transcriptional repressor 2) is a protein-coding gene located on chromosome 22.
HIC2 is a gene in humans that encodes the Hypermethylated in cancer 2 protein. This protein plays a role in regulating gene expression, and its activity may be linked to cancer development.
HIC2 acts as a transcriptional repressor, controlling the expression of specific genes.
HIC2 is also known as HRG22, ZBTB30, ZNF907.
Associated Diseases
- left ventricular noncompaction
- atrioventricular septal defect 5
- autosomal dominant coarctation of aorta
- familial thoracic aortic aneurysm and aortic dissection
- ventricular septal defect 1
- tricuspid atresia
- 22q11.2 deletion syndrome
- fallot complex-intellectual disability-growth delay syndrome
- congenital heart defects, multiple types, 6
- congenital heart defects, multiple types, 5
- cardiomyopathy, dilated, 2H
- pulmonary atresia with ventricular septal defect
- ventricular septal defect 3
- lung agenesis-heart defect-thumb anomalies syndrome
