HFE
Plays a pivotal role in regulating iron absorption, influences our body‘s iron balance and plays a crucial role in preventing iron overload disorders.
Associated Diseases
Hereditary Hemochromatosis
Did you know
Hereditary Hemochromatosis is common in individuals of Northern European descent. Approximately 1 in 200 individuals of Northern European descent carries two copies of the mutated HFE gene, making them susceptible to Hereditary Hemochromatosis.This hereditary disorder disrupts the body‘s ability to regulate iron absorption, leading to excess iron accumulation in vital organs.
The condition tends to manifest later in life, primarily affecting individuals in their 40s or 50s. Symptoms may include fatigue, joint pain, and organ damage caused by iron overload. Early detection through genetic testing is crucial, as untreated Hereditary Hemochromatosis can result in serious complications such as liver cirrhosis, diabetes, and heart problems.
Routine screening for iron levels and genetic testing for HFE gene mutations can aid in the early identification of individuals at risk. Effective management, including therapeutic phlebotomy to reduce iron levels, can prevent the progression of complications associated with Hereditary Hemochromatosis. Raising awareness about this often asymptomatic yet potentially serious condition is essential for timely diagnosis and intervention, ultimately improving the quality of life for those affected by Hereditary Hemochromatosis.
