HBE1
Description
The HBE1 (hemoglobin subunit epsilon 1) is a protein-coding gene located on chromosome 11.
Hemoglobin subunit epsilon is a protein encoded by the HBE1 gene in humans. This gene is expressed in the embryonic yolk sac, where it combines with zeta chains to form embryonic hemoglobin Gower I and with alpha chains to form embryonic hemoglobin Gower II. These embryonic hemoglobins are eventually replaced by fetal and then adult hemoglobin. The HBE1 gene is located on chromosome 11 within a cluster of five beta-like globin genes, including gamma-G, gamma-A, delta, and beta.
Epsilon-globin, also known as the epsilon chain, is a beta-type globin chain that is part of early mammalian embryonic hemoglobin.
HBE1 is also known as HBE.
