GTF3C2
Description
The GTF3C2 (general transcription factor IIIC subunit 2) is a protein-coding gene located on chromosome 2.
GTF3C2 is a protein encoded by the GTF3C2 gene in humans. It interacts with GTF3C4 and GTF3C5.
GTF3C2 is essential for RNA polymerase III-mediated transcription. It is a component of TFIIIC, a complex that initiates transcription complex assembly on tRNA. GTF3C2 is also necessary for the transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. It may contribute to stabilizing the interaction between TFIIIC2 and TFIIIC1.
GTF3C2 is also known as TF3C-beta, TFIIIC-BETA, TFIIIC110.
