GTF3C1
Description
The GTF3C1 (general transcription factor IIIC subunit 1) is a protein-coding gene located on chromosome 16.
GTF3C1 is a human protein encoded by the GTF3C1 gene. It interacts with GTF3C4.
GTF3C1 plays a vital role in RNA polymerase III-mediated transcription. It is a subunit of TFIIIC, a complex that initiates the formation of transcription complexes on tRNA. GTF3C1 is essential for the transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. It binds to the box B promoter element.
GTF3C1 is also known as TFIIIC, TFIIIC220, TFIIICalpha.
