GSTT1


Description

The GSTT1 (glutathione S-transferase theta 1) is a protein-coding gene located on chromosome 22.

GSTT1 is a human gene that encodes the enzyme glutathione S-transferase theta-1. This enzyme is part of a larger family of proteins responsible for catalyzing the conjugation of reduced glutathione to various electrophilic and hydrophobic compounds. This process is essential for detoxification, neutralizing potentially harmful substances. GSTT1 belongs to the theta class of glutathione S-transferases, which includes GSTT2. Both GSTT1 and GSTT2 share a significant sequence similarity, suggesting a common role in detoxification. The GSTT1 gene is located near the GSTT2 gene and shares a similar structure, composed of five exons with identical exon/intron boundaries.

GSTT1 is also known as -.

Associated Diseases


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