GPR89A

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Description

The GPR89A (G protein-coupled receptor 89A) is a protein-coding gene located on chromosome 1.

GPR89A is a voltage-dependent anion channel essential for the acidification and proper function of the Golgi apparatus. It contributes to counter-ion conductance, playing a crucial role in lymphocyte development likely by acting as a RABL3 effector in hematopoietic cells.

GPR89A is also known as GPHR, GPR89, GPR89B, SH120, UNQ192.

Associated Diseases

• Okt4 epitope deficiency
• combined immunodeficiency with skin granulomas
• 22q11.2 deletion syndrome
• immunodeficiency 19
• immunodeficiency 18
• trigonocephaly