GPR27
Description
The GPR27 (G protein-coupled receptor 27) is a protein-coding gene located on chromosome 3.
GPR27 is a gene that encodes a protein known as Probable G-protein coupled receptor 27. This protein plays a role in cellular signaling and is thought to be involved in brain function.
This receptor is classified as an "orphan receptor", meaning its specific ligand (the molecule it binds to) is currently unknown. However, it is suspected to be a type of amine-like G-protein coupled receptor, suggesting it interacts with signaling molecules similar to neurotransmitters.
GPR27 is also known as SREB1.
Associated Diseases
- hyperinsulinemic hypoglycemia, familial, 2
- hyperinsulinemic hypoglycemia, familial, 1
- hyperinsulinism due to INSR deficiency
- hyperinsulinism due to glucokinase deficiency
- exercise-induced hyperinsulinism
