GPR22

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Description

The GPR22 (G protein-coupled receptor 22) is a protein-coding gene located on chromosome 7.

The GPR22 gene in humans produces a protein called Probable G-protein coupled receptor 22.

GPR22 is an orphan G-protein coupled receptor, suggesting it might bind an unidentified ligand. Research indicates it operates through a G(i)/G(o) mediated signaling pathway, potentially contributing to ciliogenesis. (UniProtKB:A0A2R9YJI3, PubMed:18539757)

GPR22 is also known as -.

Associated Diseases

• hemoglobin E-beta-thalassemia syndrome
• hemoglobin D disease
• congenital dyserythropoietic anemia type 4
• diabetes mellitus, permanent neonatal 4