GPR142
Description
The GPR142 (G protein-coupled receptor 142) is a protein-coding gene located on chromosome 17.
GPR142 is a protein that in humans is encoded by the GPR142 gene. It is a probable G-protein coupled receptor, suggesting it plays a role in cell signaling.
GPR142 is an orphan receptor, meaning its natural ligand and function are currently unknown.
GPR142 is also known as GPRg1b, PGR2.
Associated Diseases
- hyperinsulinism due to INSR deficiency
- hyperinsulinism due to glucokinase deficiency
- hemoglobin D disease
- exercise-induced hyperinsulinism
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- dominant beta-thalassemia
- hyperinsulinism-hyperammonemia syndrome
- hemoglobin C-beta-thalassemia syndrome
- hemoglobin H disease
- hypoinsulinemic hypoglycemia and body hemihypertrophy
- hyperinsulinemic hypoglycemia, familial, 2
- delta-beta-thalassemia
- hyperinsulinemic hypoglycemia, familial, 1
- obesity due to melanocortin 4 receptor deficiency
- thyroid hormone metabolism, abnormal, 2
- hyperinsulinemic hypoglycemia, familial, 4
- hemoglobin E disease
- hemoglobin E-beta-thalassemia syndrome
- alpha-thalassemia-myelodysplastic syndrome
- transient neonatal diabetes mellitus
- islet cell adenomatosis