GNG12


Description

The GNG12 (G protein subunit gamma 12) is a protein-coding gene located on chromosome 1.

GNG12 is the gene that encodes for the protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 in humans.

G proteins are crucial components of transmembrane signaling systems. They function as modulators or transducers, facilitating communication across cell membranes. The beta and gamma subunits, including GNG12, are essential for the G protein's GTPase activity, enabling the replacement of GDP with GTP and mediating interactions with downstream effectors.

GNG12 is also known as HG3A.

Associated Diseases



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