GNG12
Description
The GNG12 (G protein subunit gamma 12) is a protein-coding gene located on chromosome 1.
GNG12 is the gene that encodes for the protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 in humans.
G proteins are crucial components of transmembrane signaling systems. They function as modulators or transducers, facilitating communication across cell membranes. The beta and gamma subunits, including GNG12, are essential for the G protein's GTPase activity, enabling the replacement of GDP with GTP and mediating interactions with downstream effectors.
GNG12 is also known as HG3A.