GLRA3
Description
The GLRA3 (glycine receptor alpha 3) is a protein-coding gene located on chromosome 4.
The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3 gene. The protein encoded by this gene is a subunit of the glycine receptor.
Glycine receptors are ligand-gated chloride channels that open upon binding of extracellular glycine. The specific characteristics of the channel, such as its closure rate, are determined by the combination of subunits. This receptor plays a critical role in reducing neuronal excitability and contributes to the generation of inhibitory signals at synapses. Additionally, it's involved in heightened pain sensitivity in response to increased prostaglandin E2 levels, and in cellular responses to alcohol.
GLRA3 is also known as -.
