GLRA2
Description
The GLRA2 (glycine receptor alpha 2) is a protein-coding gene located on chromosome X.
The GLRA2 gene encodes the glycine receptor subunit alpha-2, a protein that plays a crucial role in the nervous system by mediating inhibitory neurotransmission. It forms part of a chloride channel that is activated by glycine, taurine, and beta-alanine. This channel is involved in various processes, including regulating neuronal excitability, synaptic plasticity, and cellular responses to ethanol.
Glycine receptors are ligand-gated chloride channels that are activated by extracellular glycine, taurine, and beta-alanine. They contribute to the generation of inhibitory postsynaptic currents, downregulate neuronal excitability, and play a role in synaptic plasticity and cellular responses to ethanol.
GLRA2 is also known as GLR, MRXSP.