GJA9
Description
The GJA9 (gap junction protein alpha 9) is a protein-coding gene located on chromosome 1.
Gap junction delta-2 protein (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9), is a protein encoded by the GJD2 gene in humans. GJD2 is a member of the connexin gene family and is primarily expressed in mammalian neurons. Connexins group together in sets of six to form connexons, which are radially organized around a central pore. Two connexons connect to form a gap junction intercellular channel. For more information about connexins, see GJB2.
Gap junctions are clusters of closely packed pairs of transmembrane channels, known as connexons. These connexons allow for the diffusion of small molecules from one cell to its neighbor.
GJA9 is also known as CX58, CX59, GJA10.
