GIPR
GPCRs: Unlocking the Gateway for Cell Communication
Description
G protein-coupled receptors (GPCRs) are the largest and most diverse family of cell surface receptors in humans. They act as molecular gatekeepers, receiving signals from outside the cell and transmitting them to the inside, triggering a cascade of intracellular events. GPCRs are found on virtually every cell type and participate in a wide range of physiological processes, including sensory perception, hormone regulation, and neurotransmission.
Associated Diseases
Dysfunction or malfunction of GPCRs has been linked to numerous diseases, including:
- Cardiovascular diseases: Heart failure, hypertension
- Metabolic disorders: Obesity, diabetes
- Neurological disorders: Parkinson's disease, Alzheimer's disease
- Respiratory diseases: Asthma, chronic obstructive pulmonary disease
- Cancer: Breast cancer, prostate cancer
Did you Know ?
GPCRs are estimated to mediate over 30% of all drug targets, making them a key area of research in pharmaceutical development.
