GIMAP1-GIMAP5
Description
The GIMAP1-GIMAP5 (GIMAP1-GIMAP5 readthrough) is a protein-coding gene located on chromosome 7.
GIMAP1-GIMAP5 genes encode a family of GTPases that play a critical role in regulating immune cell development and function. These proteins are involved in T cell differentiation, proliferation, and apoptosis, as well as the development of natural killer (NK) cells. They are also implicated in the regulation of immune responses, including inflammation and autoimmunity.
The GIMAP genes (GIMAP1-GIMAP5) encode a family of GTPases involved in the regulation of immune cell development and function. They play a crucial role in T cell differentiation, proliferation, and apoptosis, as well as in the development of natural killer (NK) cells. GIMAP1-GIMAP5 also have been implicated in the regulation of immune responses, including inflammation and autoimmunity.
GIMAP1-GIMAP5 is also known as -.
Associated Diseases
- Okt4 epitope deficiency
- Lisch epithelial corneal dystrophy
- X-linked endothelial corneal dystrophy
- X-linked corneal dermoid
- immunodeficiency 72 with autoinflammation
- T-B+ severe combined immunodeficiency due to JAK3 deficiency
- autosomal dominant keratitis
- Schnyder corneal dystrophy
- lattice corneal dystrophy type I
- common variable immunodeficiency
- granular corneal dystrophy type I
- combined immunodeficiency with skin granulomas
- corneal dystrophy, punctiform and polychromatic pre-descemet
- combined immunodeficiency due to ZAP70 deficiency
- autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency
- isolated agammaglobulinemia
