Venous Thromboembolism

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Venous thromboembolism (VTE) involves the formation of blood clots in the veins, posing a risk of pulmonary embolism if left untreated.

Impact of Gene Variants

Genetic factors can predispose individuals to VTE by influencing blood clotting mechanisms. Mutations in genes involved in coagulation pathways, such as Factor V Leiden and prothrombin gene mutation, increase the risk of abnormal clot formation, particularly in response to triggers like surgery, prolonged immobility, or hormonal changes.

Ways to Recognize Problems

Symptoms of VTE may include swelling, pain, warmth, and redness in the affected leg, often accompanied by shortness of breath, chest pain, and rapid heartbeat in cases of pulmonary embolism. Diagnostic tests such as ultrasound, CT scans, and blood tests measuring D-dimer levels help confirm diagnosis.

Ways to Improve

Prevention and management of VTE involve lifestyle modifications, medication, and supportive therapies. Strategies include maintaining a healthy weight, staying physically active, avoiding prolonged immobility, using compression stockings, and taking anticoagulant medications as prescribed to prevent clot formation and recurrence.

Did you know

VTE affects 1-2 per 1000 people in the U.S. annually.