Cisplatin


Cisplatin, a chemotherapy medication, has been instrumental in treating various types of cancer. This article aims to delve into the mechanism of action, potential side effects, and the diverse applications of cisplatin in modern medicine.

Mechanism of Action

Cisplatin exerts its anti-cancer effects by forming platinum-DNA adducts, leading to DNA damage and triggering apoptotic cell death in cancer cells. This mechanism disrupts the replication and transcription process, ultimately inhibiting tumor growth.

Impact of Gene Variants

Genetic variations can influence an individual‘s response to cisplatin therapy. Certain gene variants may affect the metabolism and clearance of cisplatin, thereby influencing its efficacy and the risk of adverse reactions.



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.