ZNF837
Description
The ZNF837 (zinc finger protein 837) is a protein-coding gene located on chromosome 19.
ZNF837 is a human protein encoded by the ZNF837 gene located on chromosome 19. It is categorized as a C2H2-type zinc finger protein. ZNF837 shares similarities with proteins found in other mammals and even more distantly related chordates. These homologs all contain COG5048 and Zf-C2H2_2 domains, which exhibit the highest conservation rates. Human ZNF837 contains 5 Zf-H2C2 double domains and 2 COG5048 domains. The protein sequence evolves rapidly among these homologs. ZNF837 has numerous paralogs in humans, all of which are zinc finger proteins. In humans, ZNF837 has no other aliases and is located near genes MIR4754, A1BG, and RPS5.
ZNF837 is also known as -.
Associated Diseases
- Parkinson disease
- lysosomal storage disease
- Alzheimer disease
- multiple sclerosis
- COVID-19
- Dravet syndrome
