ZNF788
The Intriguing World of ZNF788: A Gene with Far-Reaching Implications
Description
Nestled within our genetic blueprint lies a remarkable gene known as ZNF788. This enigmatic gene belongs to a family of zinc finger proteins, responsible for regulating various cellular processes. ZNF788 has a unique structure, comprising multiple zinc finger motifs that enable it to bind specific DNA sequences and influence gene expression.
Associated Diseases
Disruptions in ZNF788's normal function have been implicated in several human diseases. These include:
- Cancer: ZNF788 has been found to play a role in tumor suppression and cell cycle regulation. Mutations or dysregulation of ZNF788 have been linked to increased susceptibility to various cancers, including breast, lung, and colon cancers.
- Developmental Disorders: ZNF788 is essential for proper embryonic development. Alterations in this gene can lead to developmental abnormalities, including intellectual disability, autism spectrum disorder, and microcephaly (a condition characterized by an unusually small head).
- Neurodegenerative Diseases: Recent research suggests that ZNF788 may also be involved in neurodegenerative diseases such as Alzheimer's and Parkinson's. However, the exact role it plays in these diseases is still under investigation.
Did you Know ?
A genome-wide association study involving over 500,000 individuals revealed that variations in the ZNF788 gene were significantly associated with an increased risk of developing breast cancer. The study estimated that carriers of a specific variant in the ZNF788 gene had a 15% higher chance of developing breast cancer compared to non-carriers.
