ZNF22
Description
The ZNF22 (zinc finger protein 22) is a protein-coding gene located on chromosome 10.
ZNF22 is a gene that provides instructions for making a protein called Zinc finger protein 22.
ZNF22 binds to DNA sequences containing the motif 5‘-CAATG-3‘. It is thought to be involved in regulating gene expression and may play a role in tooth development.
ZNF22 is also known as HKR-T1, KOX15, ZNF422, Zfp422.
Associated Diseases
- schizophrenia 15
- Phelan-McDermid syndrome
- X-linked retinal dysplasia
- severe early-childhood-onset retinal dystrophy
- Potocki-Lupski syndrome
- X-linked retinoschisis
- FRAXE intellectual disability
- birdshot chorioretinopathy
- late-onset retinal degeneration
- retinitis pigmentosa
- intellectual developmental disorder, X-linked, syndromic, Pilorge type