ZNF205
Description
The ZNF205 (zinc finger protein 205) is a protein-coding gene located on chromosome 16.
ZNF205 is a transcriptional repressor that regulates the expression of MPV17L. This regulation impacts genes involved in hydrogen peroxide metabolism and the mitochondrial apoptotic pathway.
ZNF205 is also known as RhitH, ZNF210, Zfp13.
Associated Diseases
- hemoglobin D disease
- hemoglobin E disease
- dominant beta-thalassemia
- delta-beta-thalassemia
- alpha-thalassemia-myelodysplastic syndrome
- hemoglobin C-beta-thalassemia syndrome
- hemoglobin E-beta-thalassemia syndrome
- hemoglobin H disease
- overhydrated hereditary stomatocytosis
- microcytic anemia with liver iron overload
- monosomy 7 myelodysplasia and leukemia syndrome 1
- hereditary elliptocytosis
- dehydrated hereditary stomatocytosis
