ZNF175
Description
The ZNF175 (zinc finger protein 175) is a protein-coding gene located on chromosome 19.
ZNF175 downregulates the expression of several chemokine receptors and inhibits HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
ZNF175 is also known as OTK18.
Associated Diseases
- hypertriglyceridemia 2
- cholesterol-ester transfer protein deficiency
- thyroid hormone metabolism, abnormal, 2
- sitosterolemia
- homozygous familial hypercholesterolemia
- isolated asymptomatic elevation of creatine phosphokinase
- hypercholesterolemia, autosomal dominant, 3
- hyperlipoproteinemia type V
- hyperlipidemia due to hepatic triglyceride lipase deficiency
- hypercholesterolemia, autosomal dominant, type B
- pancreatic triacylglycerol lipase deficiency
- pentosuria
- familial apolipoprotein C-II deficiency
- glycogen storage disease VI
