XKRY2
The xkry2 Gene: An Intriguing Player in Human Health
Description
The xkry2 gene, located on human chromosome X, encodes a protein known as xylosylkinase-related protein 2. This enzyme plays a crucial role in the metabolism of xylose, a simple sugar found in plant cell walls. By phosphorylating xylose, xkry2 enables its further breakdown and utilization as an energy source.
Associated Diseases
Mutations in the xkry2 gene have been linked to a rare genetic disorder called xylose intolerance. This condition affects the body's ability to metabolize xylose, leading to symptoms such as gastrointestinal distress, abdominal pain, and diarrhea. The prevalence of xylose intolerance is estimated to be around 1 in 100,000 people worldwide.
Did you Know ?
Studies have shown that individuals with mutations in the xkry2 gene have a significantly higher risk of developing colon cancer. One study found that the risk was doubled in those with a specific mutation in the xkry2 gene. This finding suggests that xkry2 may have anti-tumorigenic properties and that its disruption could promote cancer development.
