XKRY
Description
The XKRY (XK related, Y-linked (pseudogene)) is a pseudo gene located on chromosome Y.
XKRY is a gene located on the X chromosome that encodes a protein important for the formation of Kell blood group antigens, crucial for blood transfusions. Mutations in this gene can lead to McLeod syndrome, a rare disorder characterized by acanthocytosis, neurodegenerative issues, and increased autoimmune risk.
XKRY, also known as XK, is a protein that in humans is encoded by the XKRY gene. The XKRY gene is located on the X chromosome and encodes a protein that is expressed primarily in red blood cells. The XKRY protein is a member of the Kell blood group system and is involved in the formation of the Kell blood group antigens. These antigens are important for blood transfusions, as individuals with different Kell blood types can have severe reactions if they receive blood from a donor with a different Kell type. Mutations in the XKRY gene can cause McLeod syndrome, a rare X-linked recessive disorder that is characterized by acanthocytosis, a neurodegenerative disorder, and an increased risk of developing autoimmune diseases. The XKRY protein is a type II membrane protein that is thought to be involved in the transport of lipids or other molecules across the red blood cell membrane.
XKRY is also known as XKRY1.
