WNT8B
Description
The WNT8B (Wnt family member 8B) is a protein-coding gene located on chromosome 10.
The WNT8B gene produces the Wnt-8b protein, a member of the WNT gene family. These genes encode secreted signaling proteins involved in various developmental processes and cancer. Wnt-8b shares significant similarity with its counterparts in other species, displaying high amino acid identity to mouse, zebrafish, and Xenopus Wnt8B proteins. Its expression is confined to the developing brain, mirroring the mouse gene's expression pattern. The gene's location on chromosome 10q24 makes it a potential candidate for partial epilepsy.
WNT8B is also known as -.
Associated Diseases
- endometrial cancer
- coloboma
- Hirschsprung disease
- liver and intrahepatic bile duct neoplasm
- Miyoshi myopathy
- cancer
- split hand-foot malformation
- osteogenesis imperfecta
