WIF1
Description
The WIF1 (WNT inhibitory factor 1) is a protein-coding gene located on chromosome 12.
WIF1, or Wnt Inhibitory Factor 1, is a protein encoded by the WIF1 gene in humans. It's a lipid-binding protein that binds to Wnt proteins, preventing them from activating signaling pathways. Wnt proteins are essential for embryonic development, and WIF1's ability to inhibit their activity is crucial for proper development. WIF1 contains a WIF domain and five EGF-like domains. WIF1 is found in a variety of animals, including fish, amphibians, and mammals, suggesting its importance in development.
WIF1 is also known as WIF-1.
Associated Diseases
- carcinoma of liver and intrahepatic biliary tract
- urinary bladder carcinoma
- pancreatic ductal adenocarcinoma
