UBXN8

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Description

The UBXN8 (UBX domain protein 8) is a protein-coding gene located on chromosome 8.

UBXN8 participates in the endoplasmic reticulum-associated degradation (ERAD) pathway, a quality control mechanism that removes misfolded proteins from the endoplasmic reticulum (ER) lumen. It likely facilitates this process by linking VCP, an essential protein involved in ERAD, to the ER membrane.

UBXN8 is also known as D8S2298E, REP8, UBXD6.

Associated Diseases

• cancer