TRAT1
Description
The TRAT1 (T cell receptor associated transmembrane adaptor 1) is a protein-coding gene located on chromosome 3.
TRAT1 is a protein encoded by the TRAT1 gene in humans. It functions as a transmembrane adapter associated with the T-cell receptor.
TRAT1 plays a crucial role in stabilizing the TCR (T-cell antigen receptor)/CD3 complex on the surface of T-cells.
TRAT1 is also known as HSPC062, TCRIM, TRIM, pp29/30.
Associated Diseases
- cancer
- endometrial cancer
- breast cancer
- familial isolated congenital asplenia
- short-limb skeletal dysplasia with severe combined immunodeficiency