TONSL-AS1
Description
The TONSL-AS1 (TONSL antisense RNA 1) is a ncRNA gene located on chromosome 8.
TONSL-AS1 is a long non-coding RNA (lncRNA) that has been implicated in the regulation of gene expression. Studies have shown that it can act as a competing endogenous RNA (ceRNA) by sponging microRNAs (miRNAs), influencing the expression of target genes. This lncRNA has been linked to the development of certain cancers, such as colorectal and pancreatic cancers, where it may contribute to tumor growth and progression by regulating genes involved in cell proliferation, apoptosis, and angiogenesis.
TONSL-AS1 is a long non-coding RNA (lncRNA) that has been found to be involved in the regulation of gene expression. Studies have shown that TONSL-AS1 can act as a competing endogenous RNA (ceRNA) by sponging microRNAs (miRNAs), thereby affecting the expression of target genes. For example, TONSL-AS1 has been shown to sponge miR-145-5p, which regulates the expression of the gene TP53, a key tumor suppressor. Additionally, TONSL-AS1 has been linked to the development of various cancers, such as colorectal cancer and pancreatic cancer. It is thought to contribute to tumor growth and progression by regulating the expression of genes involved in cell proliferation, apoptosis, and angiogenesis.
TONSL-AS1 is also known as -.
