TMEM79
Description
The TMEM79 (transmembrane protein 79) is a protein-coding gene located on chromosome 1.
TMEM79 contributes to maintaining the skin's outer layer (epidermis) and its protective barrier function. It plays a key role in the secretion of lamellar granules, which are important for forming the stratum corneum, the outermost layer of the skin.
TMEM79 is also known as MATT.
Associated Diseases
- uncombable hair syndrome
- ringed hair disease
- hypotrichosis simplex
- hypotrichosis 4
- alopecia universalis congenita
- wooly hair, autosomal recessive 3
- pili bifurcati
- trichodysplasia-xeroderma syndrome
- Marie Unna hereditary hypotrichosis
- Griscelli syndrome type 3
