TMEM69
Description
The TMEM69 (transmembrane protein 69) is a protein-coding gene located on chromosome 1.
TMEM69, also known as Transmembrane protein 69, is a protein encoded by the TMEM69 gene in humans. The gene is located on chromosome 1p34.1 and spans 7.24 kb. It produces a primary mRNA transcript of 6262 bp with 3 exons. Three alternative transcripts are also predicted. The exact function of TMEM69 is not yet known, but it is believed to act as a scaffolding protein in a G-coupled protein receptor complex in Xenopus tropicalis. It forms a cluster with xtGPR54-2, IPP, and GPBP1 in scaffold_41, which is part of a G-coupled protein receptor complex that binds kisspeptin in the plasma membrane of brain cells. The protein itself is 247 amino acids long and has five transmembrane segments.
The exact function of TMEM69 is not yet understood. However, it is believed to act as a scaffolding protein in a G-coupled protein receptor complex in Xenopus tropicalis. It forms a cluster with xtGPR54-2, IPP, and GPBP1 in scaffold_41, which is part of a G-coupled protein receptor complex that binds kisspeptin in the plasma membrane of brain cells.
TMEM69 is also known as C1orf154.
