TMEM255A
Description
The TMEM255A (transmembrane protein 255A) is a protein-coding gene located on chromosome X.
TMEM255A, also known as FAM70A, is a gene that encodes a transmembrane protein located in the nuclear envelope of eukaryotic cells. The gene spans 60,555 base pairs and is located on chromosome X. It contains 9 exons and produces three transcript variants, with isoform 1 being the longest. The mRNA is 3512 base pairs long and includes 5' and 3' untranslated regions (UTRs) containing stem-loop structures. The protein encoded by isoform 1 is 349 amino acids long, with a predicted molecular weight of 38 kDa and an isoelectric point of 7.89. Compared to the average vertebrate protein, TMEM255A is rich in aspartic acid, isoleucine, proline, and tyrosine, while being relatively poor in glutamic acid and lysine.
TMEM255A is also known as FAM70A.
Associated Diseases
- major depressive disorder
- colorectal cancer
- cystic fibrosis
- systemic lupus erythematosus
- pancreatic ductal adenocarcinoma
- ulnar-mammary syndrome
