TMEM229B
Description
The TMEM229B (transmembrane protein 229B) is a protein-coding gene located on chromosome 14.
TMEM229B, also known as C14orf83, FLJ33387, Q8NBD8, Hs.509707, Hs.712258, IPR010540, and CN083_HUMAN, is a gene located on chromosome 14 at location 14q24.1. It spans 45,038 base pairs and has 3 exons in its primary unspliced transcript mRNA of 4,068 bp. There are 7 transcript variants ranging in mRNA size from 519 bp to 5008 bp. TMEM229B is highly conserved in vertebrates, including portions of the 3'UTR. The gene is flanked by phosphatidylinositol glycan anchor class H (PIGH) and PLEK2.
TMEM229B is ubiquitously expressed throughout the body with higher expression in the parathyroid, skin, and thyroid tissues. It is also moderately expressed in bone marrow, trachea, spleen, eye, brain, pancreas, mammary gland, intestine, liver, thymus, lymph node, ovarian, muscle, lung, blood, and kidney tissues.
The translated TMEM229B protein is 167 amino acids long and has a predicted molecular weight of 19,531 daltons. The protein contains a domain of unknown function (DUF1113), spanning amino acids 87 to 135.
TMEM229B is also known as C14orf83.
