TMEM17
Description
The TMEM17 (transmembrane protein 17) is a protein-coding gene located on chromosome 2.
TMEM17 is a transmembrane protein that is part of the tectonic-like complex, a structure found at the transition zone of primary cilia. This complex acts as a barrier, preventing the movement of transmembrane proteins between the cilia and the cell's outer membrane. TMEM17 plays a vital role in the formation of cilia (ciliogenesis) and in the signaling pathway of sonic hedgehog (SHH).
TMEM17 is also known as -.