TMEM169
Description
The TMEM169 (transmembrane protein 169) is a protein-coding gene located on chromosome 2.
TMEM169 is a human gene located on chromosome 2 (2q35), spanning 20,918 bases. It contains four exons and is transcribed into five alternatively spliced variants, all coding for the same protein but differing in their 5’ UTR region. TMEM169 has homologs across various species, including mammals, reptiles, amphibians, birds, fish, chordates, and even invertebrates, suggesting its importance in biological processes. The most distantly related homolog is found in Anopheles albimanus. TMEM169 exhibits highest expression in the brain, particularly the fetal brain, hinting at a potential role in neuronal development or function.
The precise function of TMEM169 remains unknown, but its high expression in the brain, especially the fetal brain, suggests a potential role in neuronal development or function.
TMEM169 is also known as -.
