TAS2R9
Description
The TAS2R9 (taste 2 receptor member 9) is a protein-coding gene located on chromosome 12.
The TAS2R9 gene encodes a protein that belongs to the family of taste receptors. These receptors are located in the taste cells of the tongue and palate. They are involved in the perception of bitter tastes and are organized in clusters on chromosome 12p13. Studies have shown that variations in this gene can affect how people perceive the bitterness of the sweetener acesulfame potassium.
This receptor plays a key role in detecting bitter tastes, primarily in the mouth and digestive system. It interacts with a signaling pathway involving PLCB2 and TRPM5, a calcium-activated ion channel, to relay the bitter taste signal.
TAS2R9 is also known as T2R9, TRB6.
