TANC2

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Description

The TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) is a protein-coding gene located on chromosome 17.

TANC2 serves as a scaffolding protein within dendritic spines, acting as a stationary postsynaptic component that attracts KIF1A-propelled dense core vesicles to these structures.

TANC2 is also known as IDDALDS, ROLSA, rols.

Associated Diseases

• Intellectual developmental disorder with autistic features and language delay, with or without seizures