SYTL4
Description
The SYTL4 (synaptotagmin like 4) is a protein-coding gene located on chromosome X.
SYTL4 is a protein that is encoded by the SYTL4 gene in humans.
SYTL4 modulates the release of hormones from dense-core granules in the pancreas and pituitary gland. It interacts with vesicles containing negatively charged phospholipids without requiring calcium.
SYTL4 is also known as SLP4.
Associated Diseases
- type 2 diabetes mellitus
- diabetes mellitus, transient neonatal, 2
- type 1 diabetes mellitus
- hyperinsulinemic hypoglycemia, familial, 2
- panhypopituitarism
- Leydig cell hypoplasia, type 1
- short stature due to GHSR deficiency
- non-acquired combined pituitary hormone deficiency with spine abnormalities
- hypoinsulinemic hypoglycemia and body hemihypertrophy
- hyperinsulinemic hypoglycemia, familial, 1
- exercise-induced hyperinsulinism
- hyperinsulinism due to glucokinase deficiency
- hyperinsulinism-hyperammonemia syndrome
