SV2A
Description
The SV2A (synaptic vesicle glycoprotein 2A) is a protein-coding gene located on chromosome 1.
SV2A, or Synaptic vesicle glycoprotein 2A, is a widespread protein found in synaptic vesicles throughout the human nervous system. It's involved in neurotransmission and is targeted by the anti-epileptic drugs levetiracetam and brivaracetam.
SV2A contributes to regulated secretion in both nerve and hormone-producing cells, specifically enhancing neurotransmission at low frequencies. It promotes vesicle fusion by sustaining the pool of vesicles readily available for release.
SV2A is also known as DEE113, SLC22B1, SV2.
