SUMO1P1


Description

The SUMO1P1 (SUMO1 pseudogene 1) is a pseudo gene located on chromosome 20.

SUMO1P1 (SUMO-1) is a small ubiquitin-like modifier protein that plays a crucial role in various cellular processes, including protein stability, subcellular localization, and signal transduction. It is involved in SUMOylation, a post-translational modification that affects the function and fate of target proteins. SUMOylation is reversible and involves a cascade of enzymatic reactions, including the attachment of SUMO1P1 to target proteins and its subsequent removal. SUMO1P1 is involved in a wide range of cellular functions, including DNA repair, cell cycle regulation, transcription, and apoptosis. Dysregulation of SUMO1P1 expression and function has been linked to various human diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

SUMO1P1, also known as SUMO-1, is a small ubiquitin-like modifier (SUMO) protein that plays a crucial role in various cellular processes, including protein stability, subcellular localization, and signal transduction. SUMO1P1 is conjugated to target proteins through a process called SUMOylation, which involves a cascade of enzymatic reactions. SUMOylation modifies the function and fate of target proteins, affecting their stability, activity, and interactions with other proteins. This modification is reversible, and the removal of SUMO1P1 from target proteins is mediated by SUMO-specific proteases. SUMO1P1 is involved in a wide range of cellular functions, including DNA repair, cell cycle regulation, transcription, and apoptosis. Dysregulation of SUMO1P1 expression and function has been linked to various human diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

SUMO1P1 is also known as PIC1L, UBL2, UBL6.

Associated Diseases



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