STK4-AS1
The stk4-as1 Gene: A Key Player in Human Health
Description:
The stk4-as1 gene, also known as the Serine/Threonine Kinase 4 Antisense RNA 1, is a non-coding RNA molecule that plays a crucial role in various biological processes. It is located on chromosome 12q24.31 and spans approximately 1.4 kilobases in length.
stk4-as1 belongs to a class of RNAs called long non-coding RNAs (lncRNAs), which are not translated into proteins but rather regulate gene expression in various ways. In the case of stk4-as1, it has been found to interact with other RNAs and proteins to influence the activity of specific genes.
Associated Diseases:
Alterations in the expression levels or function of the stk4-as1 gene have been linked to a number of human diseases, including:
- Cardiovascular disease: stk4-as1 is involved in regulating blood vessel formation and inflammation, and its dysregulation has been associated with an increased risk of atherosclerosis and other cardiovascular events.
- Neurodegenerative disorders: stk4-as1 has been shown to play a role in neuronal development and function, and its aberrant expression is associated with neurodegenerative diseases such as Alzheimer‘s and Parkinson‘s.
- Cancer: stk4-as1 is involved in regulating cell growth, proliferation, and apoptosis, and its dysregulation is commonly found in various types of cancer, including lung cancer, breast cancer, and leukemia.
Did you Know ?
According to a recent study, individuals with elevated levels of stk4-as1 in their blood may have a 35% increased risk of developing cardiovascular disease compared to those with normal levels.
