SSC5D
Description
The SSC5D (scavenger receptor cysteine rich family member with 5 domains) is a protein-coding gene located on chromosome 19.
SSC5D binds to components of the extracellular matrix and recognizes pathogen-associated molecular patterns (PAMPs) found on the surfaces of bacteria and fungi. This recognition acts as a pattern recognition receptor (PRR) that triggers the aggregation of these pathogens, thereby inhibiting the release of inflammatory cytokines. Notably, SSC5D does not exhibit direct antimicrobial activity. It is believed to contribute to the innate immune defense and maintenance of specific epithelial tissues.
SSC5D is also known as S5D-SRCRB.
Associated Diseases
- macrothrombocytopenia, isolated, 2, autosomal dominant
- thrombocytopenia 4
- autosomal dominant macrothrombocytopenia
- platelet-type bleeding disorder 15
- platelet-type bleeding disorder 10
- thrombocytopenia 2
- thrombocytopenia 7
- bleeding disorder, platelet-type, 24
- DIAPH1-related sensorineural hearing loss-thrombocytopenia syndrome
- autosomal dominant nonsyndromic hearing loss 1
- beta-thalassemia-X-linked thrombocytopenia syndrome
- thrombocytopenia 3
