SPTY2D1-AS1
spty2d1-as1: A Gene Linked to Tooth Development and Bone Disorders
Description
The spty2d1-as1 gene is located on chromosome 16 in humans. It produces a long non-coding RNA (lncRNA) molecule that plays a crucial role in the regulation of tooth development and bone formation. The lncRNA binds to specific proteins and DNA sequences, influencing the expression of genes involved in these processes.
Associated Diseases
Mutations in the spty2d1-as1 gene have been linked to several diseases, including:
- Tooth agenesis: Failure to develop one or more teeth during childhood.
- Oligodontia: The absence of six or more teeth.
- Cleft lip and palate: A birth defect involving a split in the upper lip and palate.
- Alveolar clefts: Gaps in the bone that supports the upper teeth.
- Osteogenesis imperfecta: A genetic bone disorder that leads to weak and brittle bones.
Did you Know ?
Approximately 1 in 2,000 people are affected by tooth agenesis, making it one of the most common congenital dental anomalies.
