SPDYC


Description

The SPDYC (speedy/RINGO cell cycle regulator family member C) is a protein-coding gene located on chromosome 11.

SPDYC promotes cell cycle progression by binding and activating CDK1 and CDK2. It plays a role in the spindle-assembly checkpoint, ensuring proper chromosome segregation. SPDYC is crucial for recruiting proteins like MAD2L1, BUBR1, and BUB1 to kinetochores, which are structures that attach to chromosomes during cell division. It also ensures the correct localization of the active form of Aurora B kinase in prometaphase, a critical phase of mitosis.

SPDYC is also known as RINGOC, Ringo2, SPDYE4.

Associated Diseases



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.