SPATA22
Description
The SPATA22 (spermatogenesis associated 22) is a protein-coding gene located on chromosome 17.
SPATA22 is a protein that plays a crucial role in the process of homologous recombination during meiosis I. This recombination is essential for proper chromosome pairing and exchange of genetic material, which is a fundamental step in the formation of gametes.
SPATA22 is also known as NYD-SP20, NYDSP20.
Associated Diseases
- Canavan disease
- mild Canavan disease
- Olmsted syndrome 1
- Fraser syndrome
- partial chromosome Y deletion
- spermatogenic failures 50
- spermatogenic failure 25
- male infertility with teratozoospermia due to single gene mutation
- isochromosomy Yp
- spermatogenic failure, X-linked, 2
- spermatogenic failure 48
- isochromosomy Yq
- spermatogenic failure 61
- spermatogenic failure 63
- spermatogenic failure 74
- spermatogenic failure 73
- ring chromosome Y
- 46,XX testicular disorder of sex development
