SLC41A3
Description
The SLC41A3 (solute carrier family 41 member 3) is a protein-coding gene located on chromosome 3.
SLC41A3, also known as solute carrier family 41, member 3, is a protein produced by the SLC41A3 gene in humans.
SLC41A3 is a Na(+)/Mg(2+) ion exchanger, primarily responsible for transporting magnesium ions (Mg(2+)) out of the mitochondria.
SLC41A3 is also known as SLC41A1-L2.
Associated Diseases
- cancer
- congenital hydronephrosis
- familial vesicoureteral reflux
- blue diaper syndrome
- hypoparathyroidism, familial isolated, 2
- familial isolated hypoparathyroidism due to agenesis of parathyroid gland
- primary hyperoxaluria type 2
- congenital primary megaureter
- hypomagnesemia 7, renal, with or without dilated cardiomyopathy
- renal dysplasia
- renal hypomagnesemia 2
- nephrolithiasis susceptibility caused by SLC26A1
