SLC35C2
Description
The SLC35C2 (solute carrier family 35 member C2) is a protein-coding gene located on chromosome 20.
SLC35C2 is a protein produced by the SLC35C2 gene in humans. Oxygen levels are vital in regulating how cells invade other tissues, which happens during early pregnancy when the trophoblast cells invade the uterus, as well as during cancer development and spread. This gene, which is controlled by oxygen levels, is activated in trophoblast cells with low oxygen and is found in higher amounts in ovarian cancer. There are two different forms of the protein produced from this gene.
This protein is thought to be involved in the cellular response to low oxygen levels (hypoxia). It might function as a transporter for GDP-fucose, a molecule needed for adding fucose sugars to other molecules. This transporter could compete with another transporter (SLC35C1) for the same molecule. Alternatively, SLC35C2 could directly enhance the addition of fucose to the Notch protein, which is important for signaling between cells. These actions are essential for normal Notch signaling in mammals.
SLC35C2 is also known as BA394O2.1, C20orf5, CGI-15, OVCOV1.
